Rhinocort 64 mikrogram
Inhalation of high doses of corticosteroids may lead to suppression of the hypothalamic-pituitary-adrenal HPA axis function.
If any of the following happen to you, stop using Rhinocort Aqua and talk to your doctor straight away: They also reduce cytokines, leukotrienes and chemokines e. The bottle is then held upright, with one finger held on either side of the nozzle. Find medicines from the same company.
The bottle is then held upright and the nozzle pumped up and down several times times spraying into the air, until an even mist is seen. In animal reproduction studies, corticosteroids such as budesonide have been shown to induce malformations cleft palate, skeletal malformations.
The metabolism of budesonide is primarily mediated by CYP3A enzymes. Two applications of 64 micrograms into each nostril each morning or If good effect is achieved, one application of 64 micrograms. At clinically recommended doses, the pharmacokinetics of budesonide are dose-proportional and plasma exposure is correlated to the weight of the patient.
As with other drugs the administration of Rhinocort during pregnancy requires that the benefits for the mother are weighed against the risk for the foetus.
The terminal half-life of budesonide after inhalation is approximately 2. A reduction of the budesonide dose could be considered. These effects are much less likely to occur than with oral corticosteroids and may vary in individual patients and between different corticosteroid preparations.
Produktresumé (Summary of Product Characteristics, SmPC)
Use in children Rhinocort Aqua is not recommended for use in children. No special requirements for disposal.
Not all pack sizes may be marketed. A reduction of the dose may also be considered. Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Næsespray, suspension 64 mikrogram/dosis
Animal studies have also identified an involvement of excess prenatal glucocorticosteroids in increased risk for intrauterine growth retardation, adult cardiovascular disease and permanent changes in glucocorticoid receptor density, neurotransmitter turnover and behaviour at exposures below the teratogenic dose range.
Elimination The metabolites are excreted as such or in conjugated form mainly via the kidneys.
Pump the nozzle up and down several times timesspraying into the air until an even mist is seen. Each bottle of Rhinocort Aqua contains or sprays. If you are not sure if this applies to you, talk to your doctor or pharmacist before using Rhinocort Aqua.
However these animal experimental results do not appear to be relevant in humans at the recommended doses.