Simvastatin reaction with other drugs

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Doses greater than 40 mg have not been studied in this population. Men's Health Subscribe to the Men's Health newsletter for the latest on disease prevention, fitness, sex, nutrition, and more from WebMD. If the dose of simvastatin is changed or discontinued, the same procedure should be repeated.

Thus, simvastatin is much more susceptible to interactions based on CYP3A4 inhibition than atorvastatin, despite both drugs being primarily metabolized by CYP3A4. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule.

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Keep all medications away from children and pets. These medications are not usually taken together. Interactions See also How to Use section.

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It belongs to a group of drugs known as " statins. A total of drugs brand and generic names are known to interact with simvastatin. The benefits of the combined use of simvastatin with the following drugs should be carefully weighed against the potential risks of combinations: This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol.

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All patients recovered without sequelae. Safety Announcement, June 8, Use the pill finder tool on RxList. In a week, controlled study in adolescent boys and girls who were at least 1 year post- menarcheyears of age Do not use if you are pregnant.

You are about to visit a website outside of eMedicineHealth. In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure.

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This is not a complete list of possible side effects. Because statins decrease cholesterol synthesis and possibly the synthesis of other biologically active substances derived from cholesterol, ZOCOR may cause fetal harm when administered to a pregnant woman. In Canada - Call your doctor for medical advice about side effects.

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If these rare effects occur, talk to your doctor. Simvastatin 20 mg-TEV round, pink, imprinted with 93,


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