Efficacy of zolpidem in insomnia

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Patients received placebo or one of the zolpidem doses for 31 consecutive nights, followed by 4 nights of single-blind placebo administration. J Clin Psychopharmacol ; 10 3: Imidazopyridines in sleep disorders. Sleep ; 14 5: J Am Stat Assoc ; Cookies We use cookies to improve your experience with our site. Zolpidem in the treatment of transient insomnia: Langtry HD, Benfield P. There was no significant difference between the two zolpidem groups. Comparative in vivo and in vitro regional selectivity of central omega benzodiazepine site ligands in inhibiting 3H flumazenil binding in the rat central nervous system.

Rebound insomnia and newer hypnotics. Kaplan EL, Meier P.

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J Int Med Res ; J Pharmacol Exp Ther ; 2: Regression models and life tables. J Sleep Res ; 1: Subjective versus objective evaluation of hypnotic efficacy: This service is more advanced with JavaScript available, learn more at http: It was concluded that administration of nightly doses of zolpidem 10mg to patients with chronic insomnia for 31 nights resulted in a continuous and significant reduction in SSL and in a persistent increase in SST, without the induction of tolerance during, or rebound insomnia after, this period.

Treatment of sleep maintenance insomnia in older adults.

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This multicentre, double-blind, randomised, placebo-controlled, parallel-group study compared the subjective hypnotic efficacy of nightly doses of zolpidem 10mg or zolpidem 15mg with that of placebo in patients with chronic insomnia.

J Clin Psychiatry ; 53 6: Comparative autoradiographic distribution of central omega benzodiazepine modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem. Long-term treatment of insomnia with zolpidem. Dose response effects of zolpidem in normal geriatric subjects.

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Non-parametric estimation from incomplete observations. Psychol Aging ; 3: Cite article How to cite?

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