Anticholinergics to treat clozapine withdrawal
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. Reinstitution of quetiapine resolved the symptoms.
Withdrawal Symptoms 11 Dilsaver, S.
Reintroduction of quetiapine resolved the symptoms. Protracted akathisia after risperidone withdrawal. Am J Psychiatry, 3 Treatment of the serotonin syndrome with cyproheptadine. Case report of catatonia after abrupt discontinuation of clozapine. However, they note that increased risk of adverse events occurs when the patient is taking two or more antipsychotic medications simultaneously, as one would during plateau cross-titration. PubMed Link In cases in which TD is an adverse effect from use of classical antipsychotics, the authors recommend discontinuation of classical antipsychotic treatment, but substituting them with second-generation antipsychotics to reduce the risk of withdrawal-onset TD.
The patient received a diagnosis of serotonin syndrome attributed to abrupt clozapine withdrawal with concomitant use of citalopram. In this case report, abrupt discontinuation of clozapine led to catatonia and autonomic instability, which resolved upon re-initiation of clozapine treatment. Neurosciences Riyadh20 4 This case report documents a patient prescribed haloperidol who developed parkinsonism and akathisia.
Isolated oculogyric crisis on clozapine discontinuation. Pharmacol Biochem Behav, 75 1 The results of arterial blood gas analysis were normal, and the results of serum and urine toxicology studies were negative.
Why and how people decide to stop taking prescribed psychiatric medication: Treatment of withdrawal dyskinesia. PubMed Link Although many withdrawal symptoms may be related to cholinergic rebound, rare cases of neuroleptic malignant syndrome have been observed and may be due to compensatory reactions in the dopaminergic system.
Sudden akathisia after a ziprasidone dose reduction. Purchase access Subscribe to Learning for one year.
Supersensitivity psychosis in a case with clozapine tolerance. Almost half of the consumers in the study reported that their doctors did not communicate regarding how long they would need to be on the medication. The authors argue that the lack of efficacy of risperidone and quetiapine when compared with olanzapine as demonstrated in the CATIE study could be due to supersensitivity psychosis rather than simple lack of efficacy. Green, MD 2,3 ; et al Joseph D.
Rebound insomnia after abrupt clozapine withdrawal. Herein, we describe a case of serotonin syndrome that developed with the abrupt withdrawal of clozapine with concomitant use of citalopram hydrobromide, a selective serotonin reuptake inhibitor.